| NIDCD R01 (general investigator-initiated) | Investigator-initiated research projects in deafness and other communication disorders, with NIDCD applying its institute-specific funding policy to recommended budgets. | Up to 5 years of support | Modular budgets at or below $250,000 direct costs per year are generally funded at 100% of the recommended level; categorical budgets above $250,000 direct costs per year are generally funded at 85% of the recommended level | Established or mid-career investigators, and early-stage investigators with sufficiently developed, hypothesis-driven research programs in communication disorders |
| NIDCD Low Risk Clinical Trials in Communication Disorders (R01) | Support low risk clinical trials in communication disorders that do not require FDA IND or IDE authorization | Maximum project period 5 years | Up to $500,000 in direct costs per year | Established clinical investigators and teams prepared to run low-risk clinical trials in communication disorders |
| NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01) | Support research that translates basic science discoveries into clinical applications for communication disorders | Maximum period of 5 years, with a total of no more than 5 years of support across this and prior NOFOs for the initiative | Maximum funding per grant must be less than $500,000 direct costs per year unless prior approval from NIDCD is obtained; requesting $500,000 or more in any year requires contacting NIDCD at least 6 weeks before submitting | Investigators with mature basic research findings ready for translation into clinical practice, typically mid-career to established clinical or translational scientists |
| Advancing HIV/AIDS Research within the Mission of the NIDCD (R01) | Support HIV/AIDS-related research that aligns with the NIDCD mission in communication disorders | Maximum project duration of 5 years | Application budgets are capped at $499,999 in direct costs annually | Investigators with established HIV/AIDS research programs that incorporate communication disorders within the NIDCD mission |
| NIH R21 Exploratory/Developmental Grant (general NIH-wide) | Support exploratory and developmental research projects with limited preliminary data, allowing investigators to explore novel ideas or new model systems | Up to 2 years project period | Up to $275,000 total direct costs for the two-year project period, with no more than $200,000 in direct costs in any single year | Investigators at any career stage seeking to test high-risk, high-reward ideas, often including early-stage or established investigators pursuing new directions |
| NIDCD Early Career Research (ECR) Award (R21 Clinical Trial Optional) | Support early career investigators in communication disorders through exploratory or developmental research projects, with clinical trial optional | Maximum of 3 years of support | Up to $375,000 total direct costs over a maximum of 3 years, with no more than $125,000 in direct costs per year | Early career investigators in auditory and communication sciences, typically within 10 years of their terminal degree or clinical training, depending on the specific FOA definition of early career |
| NIH Pathway to Independence Award (Parent K99/R00, Independent Clinical Trial Not Allowed) | Facilitate a timely transition of outstanding postdoctoral researchers from mentored positions to independent, tenure-track or equivalent faculty positions through a two-phase career development and research award | Up to 5 years of total support in two phases: up to 2 years in the mentored K99 phase and up to 3 years in the independent R00 phase, intended to be continuous | For the independent R00 phase, total costs may not exceed $249,000 per year, including salary, fringe benefits, research costs, and indirect costs | Advanced postdoctoral researchers ready to transition to independent, tenure-track (or equivalent) faculty positions, typically within 4 to 6 years of PhD or clinical doctorate completion, depending on NOFO-specific eligibility rules |